ISO CON 90 Complete monitoring system


Adaptable, specialised air monitor for isolators used in highly regulated industries

The ISO-CON-90 system is a complete viable air monitoring solution for RABs and isolators. 

The ISO-90 monitoring head, which forms part of the system, features the high efficiency slit-to-agar method. The head,  which remains inside the critical area so reducing contamination risk, takes up minimal space within the isolator, as the pump and control unit are housed externally within the ISO-CON flow control unit.  The ISO-CON control unit has a touchscreen display, providing an intuitive user interface.

The ISO-CON's built-in powerful vacuum pump allows the smooth running of the ISO-90 head from a distance of 10+ metres, which means it is possible to situate the ISO-CON away from the head in a more convenient location.  The exhaust for the pump exits from the base of the ISO-CON, passing through a H14 HEPA filter.

The run parameters (time, % plate, delayed start, username and location) are set up using the ISO-CON, which also stores run results for uploading to a LIMS system.  Communication is by means of USB or Ethernet, with Ethernet allowing the ISO-CON to communicate via MODBUS into a software system such as SCADA.

The option to mount a secondary remote screen, on or close to the isolator is available, allowing the ISO-CON to be sited away from the process environment.  A control cable and hose connects the ISO-CON unit to the ISO-90 head and special glands/ports are available, designed to fit into a standard 1 1/2" Tri-Clover fitting as shown in the image.

ISO 90 Datasheet

ISO 90 Brochure

ISO 90 Overview Video


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The most effective way to achieve Annex 1 compliance could be to stay with your existing, proven, trusted and validated agar based methods

Very low d50 values

Exceptional biological efficiency

ImpactAir air monitors are based on the slit-to-agar method, which has very low d50 values of around 0.5µ with exceptional biological efficient and the ability to easily count real viable microbial events in CFU while being able to identify to species level.

ImpactAir Technology

Twin impingement probability reduced

Air is drawn at high speed through a narrow inlet. Particles and microbes are impacted on to agar in a rotating Petri dish.  Fresh agar is presented constantly, significantly reducing the chance of multiple microbes appearing as a single colony after incubation.

Time Correlated Results

Continuous monitoring using a 9cm agar plate

The rotating agar plate means results are time correlated. Whilst not timed to the second, localised growth on the plate can be time estimate based on its position on the plate.


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Asked Questions

How much air should we sample?

Typical requirements suggest 1,000 litres per air sample in high risk areas, such as: grade A filling lines, grade B clean rooms, operating theatres etc. As the criticality of the area reduces, the sample size can be reduced. The aim is to achieve a representative sample; so where higher counts would be expected, a smaller sample produces a more realistic number of cfu to count.

Should I use contact plates or Petri dishes for environmental air monitoring?

SAS samplers were originally designed for Contact plates, however, a Petri dish option has been available for a number of years. It is really a personal choice, although this should be decided at time of purchase, as the sampler will be specifically configured for the plate type chosen. There are advantages for each version and we would be happy to discuss your specific needs.

Can I autoclave my SAS sampler?

No, do not put your SAS sampler in a steam autoclave. The only part that can be autoclaved is the drilled head. The unit can be wiped with alcohol wipes to decontaminate it. The only other exception is the SAS Pinocchio, parts of which can be autoclaved.

How frequently should my SAS air sampler be calibrated?

Cherwell Laboratories recommends every 12 months and we will send a reminder for the month it is due. For some situations local procedures demand more frequent recalibrations so Cherwell is happy to offer tailored recalibration date labelling and reminders on request.

Why might I want gamma irradiated media?

The sterility of the packaged medium is assured and all but the outer layer of packaging is also sterile. Thus the risk to the environment to be sampled is greatly reduced. There is an additional benefit that the additional packaging and process extends the room temperature shelf life. This can be sufficient reason for small or irregular users to prefer irradiated.

What is the maximum exposure time for settle plates?

Settle plates are used to monitor the level of viable particles in the environment through a process of passive air sampling. A viable particle settles on agar plates at a rate dependent on its characteristics and the airflow in the environment.

EU GMP Guide Annex 1 has recommended that 90mm settle plates can be exposed in cleanroom environments for up to 4 hours. However, agar plates may dry out during long exposures where the rate of air exchange is high. So, it might be necessary to use deep filled settle plates, or replace the settle plate after a shorter time to ensure satisfactory growth promotion after exposure.

Is it OK to store prepared media in the fridge?

The storage condition for the majority of our prepared media is Ambient not exceeding 25ºC, the exception being a couple of very specialist products.

We have never specified storage in a fridge for our general media as this causes excessive condensation and can result in a very wet agar surface. This makes the product impossible to use.

What is the difference between general purpose and selective growth media?

General purpose media have nutrients that support the growth of most non fastidious culturable microorganisms. Selective growth media contain components that will inhibit the growth of some types of microorganisms, while supporting the growth of others.

General purpose media, such as Tryptone Soya Agar, are used to produce total counts. While selective media, such as XLD for Salmonella species, are used to test presence/absence of specific types of microorganism.


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The best products prepared for you

Our Redipor® media products are batch tested, QC certified and delivered when you need them


Bespoke accessories and services

We provide additional equipment or services to make your environmental monitoring more effective


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The Pharmaceutical and Cleanroom Industry's Guide to Prepared Culture Media

A guide to understanding the logistics, best practices and breadth of available prepared media options for varying applications.


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